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It is mainly used for treatment of cough, reversed flow of qi, warm malaria, cold and hot contacts in the skin, women with uterine bleeding and infertility, all sore ulcers; and sores. Boil the herb to drink. Contraindications for Angelica polymorpha : excessive use causes tiredness, drowsiness, and other reactions. Stopping the medicine leads to disappearance of these symptoms.

Allergic reaction: not suitable for persons with menorrhagia, bleeding tendency, yin deficiency, internal heat, and loose stools or diarrhea. Not to be consumed by persons with hot bleeding tendencies. To be consumed with caution by persons with wet fullness and bloating. It is mainly used for treatment of rheumatism, joint ache caused by wind and dampness, muscle paralysis, muscle spasm, and jaundice. It stops perspiration, dispels heat, helps digestion, and is used in decoctions.

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Long-term consumption leads to lightening of the body, extension of years, and satiety. Another name is mountain thistle, it grows in valleys.

Hara (tanden)

Long-term consumption leads to calming of the five viscera heart, spleen, liver, lungs, and kidneys , lightening of the body, and extension of years. According to Compendium of Materia Medica, the seed has a sweet taste and a neutral nature. The processed herb is used for treatment of biliary system weakness, insomnia, polydipsia, and sweating. Its raw form is used for treatment of heaty biliary system and accompanying drowsiness. It is also the drug for treatment of the diseased accupoints: liver meridian of foot—Jueyin, and gallbladder meridian of foot—Shaoyang. Contraindications for Ziziphus jujube: to be consumed with caution by persons with impure smoldering fire and those with chronic diarrhea.

Not to be used with Fang Ji Radix Stephaniae tetrandrae. It is mainly used to treat cough with dyspnea, internal injury, make up for deficiency, dispel impure qi, and relieve obstruction in the nine orifices ears, eyes, mouth, nose, urethra, and anus. It is beneficial for wisdom, and makes one clever and not forgetful.

It strengthens ambition and resolve, and multiples strength. The name of the name of the leaf is Small Grass. Another name is Fine Grass. According to compendium of Materia Medica: it has a bitter taste and warm nature and non-toxic. It is mainly used to treat forgetfulness. Contraindications for Polygala tenuifolia: persons with gastritis and gastric ulcer should use with caution. Qi Fu Yin is used for treatment of heart and qi deficiency, treatment of neurasthenia, and treatment of age-related dementia. It has effects on benefitting qi, supplementing the blood, nourishing the heart, and calming the spirit.

Persons who have heat syndrome and no weakness in qi should not consume. The underlying molecular mechanisms are incompletely understood, but may involve atherosclerosis, vascular dysfunction, hypertension, type 2 diabetes, history of cardiac disease, and total homocysteine, and possibly, lack of erythropoietin formation by the kidney.

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Advertisement Hide. Download PDF. Open Access. First Online: 07 February Introduction Dementia is a progressive syndrome characterized by memory deficits, cognitive impairment, and deterioration in emotional control and social behavior [ 1 , 2 ]. The loss in cognitive function is more than what is typically experienced in normal aging, and results from damage caused by the disease process, such as Alzheimer disease AD , Parkinson disease PD , and traumatic brain injury TBI [ 3 ].

The symptoms of dementia may be linked with alterations in neuroplasticity in corticolimbic brain regions. In particular, divergent responses have been reported; neuronal atrophy and synapse loss in the prefrontal cortex and hippocampus, and neuronal hypertrophy and increased synaptic density in the amygdala and nucleus accumbens are found [ 5 ]. Not everyone with MCI will progress to dementia, but individuals with MCI develop dementia at higher rates than those with normal cognition [ 6 , 7 ].

Table 1 Herbs used in Qi Fu Yin.

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Open image in new window. Anemia is a common finding in patients with CKD. Analyses of baseline data from adults with chronic kidney disease indicate that the prevalence of cognitive impairment is higher among those with lower eGFR, and this association is independent of traditional vascular risk factors, but rather, related to anemia [ 23 ].

The kidneys produce a glycoprotein hormone, erythropoietin Epo , in response to hypoxia.

Into the Sea of Qi

It stimulates the production of red cells in the bone marrow and has been used for the treatment of anemia in humans [ 24 ]. Epo acts through a specific erythropoietin receptor EpoR on the surface of red cell precursors in the bone marrow and facilitates their transformation to mature red blood cells. Kidney dysfuntion may therefore lead to anemia, brain energy crisis, and slow excitotoxicity. Recent study shows anemia is associated with risk of dementia in older adults [ 25 ]. This could be a basis for the link between the kidneys, marrow, and brain in TCM theory.

These pathways are not only associated with red blood cell proliferation but also vasodilation [ 27 ] and insulin-sensitization [ 28 ]. Indications for Qi Fu yin Qi Fu Yin is used for treatment of heart and qi deficiency, treatment of neurasthenia, and treatment of age-related dementia. This can be divided into 2 servings per day, to be taken on an empty stomach, when warm. Review in months. Compliance with Ethical Standards Conflict of Interest The authors have no conflicts of interest to declare. Neurology 63 7 — Ann Intern Med 5 — IArchives of Neurology 66 3 — Ritchie K, Lovestone S The dementias.

Lancet — Rev Neurosci 22 5 — Clin Geriatr Med 29 4 — JAMA 18 — Lancet — CrossRef Google Scholar. Bing W Huangdi Neijing Inner canon of the yellow emperor.


China Google Scholar. Bai D, Song J Plasma metabolic biomarkers for syndrome of phlegm and blood stasis in hyperlipidemia and atherosclerosis.

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J Tradit Chin Med 32 4 — Hypertension 46 1 — Lee M, Ovbiagele B Reno-cerebrovascular disease: linking the nephron and neuron. Expert Rev Neurother 11 2 — Mogi M, Horiuchi M Clinical interaction between brain and kidney in small vessel disease. Cardiol Res Pract — J Neurol Sci 1 — J Cereb Blood Flow Metab 32 2 — Neurology 64 7 — J Neuroimmunol 1 — Kidney Int 64 2 — Stroke 33 9 — Clin J Am Soc Nephrol 6 2 — Eur J Clin Investig 35 s3 — Neurology 81 6 — Google Scholar. Neurol Res 36 3 — Eur J Pharmacol — Cell Rep 13 9 — Int J Mol Sci 17 5 :e Eur Spine J 18 3 — Nature — Science — Mol Cell Biol 20 8 — J Cereb Blood Flow Metab 22 5 — Neurotherapeutics 6 1 — Jassal S, Devins G, Chan C, Bozanovic R, Rourke S Improvements in cognition in patients converting from thrice weekly hemodialysis to nocturnal hemodialysis: a longitudinal pilot study.

Kidney Int 70 5 — Neurochem Int 41 2 — Metab Brain Dis 22 3—4 — Metab Brain Dis 24 1 — Clin Epidemiol — Neurol Res 28 6 — J Intern Med 4 — N Engl J Med 13 — Stroke 36 6 — J Alzheimers Dis 35 4 — Brod SA Unregulated inflammation shortens human functional longevity. Inflamm Res 49 11 — Purkayastha S, Cai D Neuroinflammatory basis of metabolic syndrome. Mol Metab 2 4 — Farooqui AA Neurochemical aspects of neurotraumatic and neurodegenerative diseases.

What are meridians in Chinese Medicine?

Springer, New York. Academic Press, Amsterdam. J Neuropathol Exp Neurol 67 1 — Neuroscience 3 — Eur J Heart Fail 9 10 — J Neurol Sci 1—2 — Am J Geriatr Cardiol 16 3 — Farooqui AA Phytochemicals, signal transduction, and neurological disorders. Tachjian A, Maria V, Jahangir A Use of herbal products and potential interactions in patients with cardiovascular diseases. The development came as the U. During the G summit over the weekend in Japan, U. President Donald Trump and Chinese President Xi Jinping agreed to restart talks and not impose new tariffs on each other's goods.

The numerous overlapping sovereign claims to islands, reefs and rocks have turned the waters into an armed camp. Beijing holds the lion's share of these features with approximately 27 outposts peppered throughout. In May, CNBC learned that China quietly installed anti-ship cruise missiles and surface-to-air missile systems on three of its fortified outposts west of the Philippines in the sea.

By all accounts, the coastal defense systems represent a significant addition to Beijing's military portfolio in one of the most contested regions in the world. According to U. The Spratlys, to which six countries lay claim, are located approximately two-thirds of the way east from southern Vietnam to the southern Philippines.